Split (2)

train · 48.9k rows

Subsets and Splits

No community queries yet

The top public SQL queries from the community will appear here once available.

ID stringlengths 13 17	question stringlengths 88 1.13k	answer stringlengths 6 156	reference_sequence stringlengths 4.1k 4.1k	variant_sequence stringlengths 4.1k 4.1k
Task1_train_48400	This mutation is located on Chromosome 22. Is it associated with a disease or is it a benign polymorphism?	Benign	CACACACAAAAGAAAAAAGCTATGGAACAATGATATAAATGAAGATATATTTAGTACAGCTGTACAATGTGTTGTGTTTTAAACTAAGTGCTATTACAAAAGAGTAAAAAATTTTAAAAATTAAAAACTTGGTAAAGCAAGAAAGTTAAACTAAGGTTAATTTTCTTTTTTTTTTTTTTTGATAAGAGTCAGGATCTGTTGCCCGGGCTGGAGTGCAATGGCCCGATCTCCGCTCACCGCAACCTCCCTCCCAGGTTCAAGGGCTTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAAGTAATAGATCCATTACAT...	CACACACAAAAGAAAAAAGCTATGGAACAATGATATAAATGAAGATATATTTAGTACAGCTGTACAATGTGTTGTGTTTTAAACTAAGTGCTATTACAAAAGAGTAAAAAATTTTAAAAATTAAAAACTTGGTAAAGCAAGAAAGTTAAACTAAGGTTAATTTTCTTTTTTTTTTTTTTTGATAAGAGTCAGGATCTGTTGCCCGGGCTGGAGTGCAATGGCCCGATCTCCGCTCACCGCAACCTCCCTCCCAGGTTCAAGGGCTTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAAGTAATAGATCCATTACAT...
Task1_train_48401	A variant was discovered on Chromosome 22. Please indicate if this mutation results in a known disease or if it's non-harmful.	Benign	ATAATTGATGAGAAACCTTGATAGAAAACTAAACCCACATTTTATAGTAACATAAAGGCAATAATGGATGACGTTAATCCTTCTCTGTCCGCCATCAGAAGATTTGATACATCTTTGTTGAGGTATTATATGATCGTCCTCTAAACTTTGAAATAATTAACAGAAGGTAAGTCCTGCTGTGATGGCCATATAAAAGTTTACTTAAACCTTTTTTTTGTTTGTTTAAATAAAAGGCGATGTAGATACTGGTAGAGCTTGTTGCTCATGTTACAGAATATACAGCTTTATAAACTTTAATTTCTCAACAAATAAATTGACTA...	ATAATTGATGAGAAACCTTGATAGAAAACTAAACCCACATTTTATAGTAACATAAAGGCAATAATGGATGACGTTAATCCTTCTCTGTCCGCCATCAGAAGATTTGATACATCTTTGTTGAGGTATTATATGATCGTCCTCTAAACTTTGAAATAATTAACAGAAGGTAAGTCCTGCTGTGATGGCCATATAAAAGTTTACTTAAACCTTTTTTTTGTTTGTTTAAATAAAAGGCGATGTAGATACTGGTAGAGCTTGTTGCTCATGTTACAGAATATACAGCTTTATAAACTTTAATTTCTCAACAAATAAATTGACTA...
Task1_train_48402	A variant found on Chromosome 22 is being studied. Please analyze its biological impact: is it benign or pathogenic, and what condition might it cause?	Benign	TCTGTCACCCAAGCAGGAGTGCAGTAGGGCAAACATGGCTCACTGCAACCTCAAATTCTTGGGCTCAAGGGATCCTCCTCCCTCAGTCCCAAGTAGCTGGGACTATCGGCATGTGCGACCATACCTGGCTAATGTTTTCTTTTTGGTAGGGACGGGTGTCTCACTTTCTTGCCCAGTCCAGTCTTGGAACTCCTGGGCTCAAGTGATCCTCCTGCCTTGGCCTCCCAAAGTGCTGGGATCACAGGCATAAGTTACTGTGCTCAGCCTGGTTTGACTTAATAGTCCTAGAGGCCCTGTCCCAACCATACAACCTTGGGCAT...	TCTGTCACCCAAGCAGGAGTGCAGTAGGGCAAACATGGCTCACTGCAACCTCAAATTCTTGGGCTCAAGGGATCCTCCTCCCTCAGTCCCAAGTAGCTGGGACTATCGGCATGTGCGACCATACCTGGCTAATGTTTTCTTTTTGGTAGGGACGGGTGTCTCACTTTCTTGCCCAGTCCAGTCTTGGAACTCCTGGGCTCAAGTGATCCTCCTGCCTTGGCCTCCCAAAGTGCTGGGATCACAGGCATAAGTTACTGTGCTCAGCCTGGTTTGACTTAATAGTCCTAGAGGCCCTGTCCCAACCATACAACCTTGGGCAT...
Task1_train_48403	This sequence variant lies on Chromosome 22. Is it clinically significant, and what condition might it cause if any?	Benign	GACTTCCTGACAAAAGAAGCAAGAGTCTCCGTGTCTGCAGCATTTCTCCATTCTGTCTCTGCCATCAGAGGAATTTTAAAGCAAAGCTCTGATTATAATTTTGTACCTCAGAGATGTCAGTGACAAACCATCGCCTGTTGGATAAAGTCCATATTTCTTAGCTGTCATTCAGGTTCCTCCATGGTCCTGTCCTCACTGACCTTCTATTCTTCATGGGCACTCTGCATTAATTAAACAGGGCTCTGTCCTTATCTTCTTTTTTTTCTGTCTCTGTGCTTTTGCCTGCATTGTGTCTTCTGTGTACCCTTCGCCTGCCAAAA...	GACTTCCTGACAAAAGAAGCAAGAGTCTCCGTGTCTGCAGCATTTCTCCATTCTGTCTCTGCCATCAGAGGAATTTTAAAGCAAAGCTCTGATTATAATTTTGTACCTCAGAGATGTCAGTGACAAACCATCGCCTGTTGGATAAAGTCCATATTTCTTAGCTGTCATTCAGGTTCCTCCATGGTCCTGTCCTCACTGACCTTCTATTCTTCATGGGCACTCTGCATTAATTAAACAGGGCTCTGTCCTTATCTTCTTTTTTTTCTGTCTCTGTGCTTTTGCCTGCATTGTGTCTTCTGTGTACCCTTCGCCTGCCAAAA...
Task1_train_48404	A variant has been detected on Chromosome 22. What is its effect — pathogenic or benign? If pathogenic, name the disease.	Benign	CTGCAGTCCGGGAACCCAGAGGAGAAAGCAGCTCACTACCTCTTCTCACTCGAGCAAGGGCGGGTAAAGAAAGCAGGAGATGCGGGCTGGGCGCGGTGGCTCAGGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCGGATCACCTGAAGTCAGGAGTTGGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAACACAAAAATTAGCTGGGTGGGGTGGTGGGTACCCGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCAAAAT...	CTGCAGTCCGGGAACCCAGAGGAGAAAGCAGCTCACTACCTCTTCTCACTCGAGCAAGGGCGGGTAAAGAAAGCAGGAGATGCGGGCTGGGCGCGGTGGCTCAGGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCGGATCACCTGAAGTCAGGAGTTGGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAACACAAAAATTAGCTGGGTGGGGTGGTGGGTACCCGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCAAAAT...
Task1_train_48405	This mutation on Chromosome 22 may be significant. Is it associated with any clinical condition, or is it benign?	Benign	CAAAAGGGAGGCAGGAAGCAGGAGACAGCCGGGTTGCCCCCAGCCAGGAGGAGGAGCACAGGCCCCAGGGCTGGACAGTGGAGGTGGGGTGACATGATACTCCGCAGAGCTCCGCCCACCCTGTATGCTGACAGGTGCCTGTTAGAGTGTGCTCTGATTCCTCTCCCTCCACCTTCACTGGATCCACCCAAAGTCCTGGGCTCTGGAAAGTGAGGGGCTGAGTCAGACCTAGCAGCCCTGCAGGTCAGTTCCTGGACCAGTCCTTTAAGACGACAAACCCTCCCTAACTATCAAACCCACCAAACGGGCAGGACCAGGCA...	CAAAAGGGAGGCAGGAAGCAGGAGACAGCCGGGTTGCCCCCAGCCAGGAGGAGGAGCACAGGCCCCAGGGCTGGACAGTGGAGGTGGGGTGACATGATACTCCGCAGAGCTCCGCCCACCCTGTATGCTGACAGGTGCCTGTTAGAGTGTGCTCTGATTCCTCTCCCTCCACCTTCACTGGATCCACCCAAAGTCCTGGGCTCTGGAAAGTGAGGGGCTGAGTCAGACCTAGCAGCCCTGCAGGTCAGTTCCTGGACCAGTCCTTTAAGACGACAAACCCTCCCTAACTATCAAACCCACCAAACGGGCAGGACCAGGCA...
Task1_train_48406	Assess the clinical impact of this variant found on Chromosome 22. State whether it’s pathogenic or benign, and the disease if applicable.	Benign	GAGCCATGATCATGCCACTGCACTATTGCCCATGCCAGTCTGGGCAAGAGACTGAGACCCTGTCTCAAAAAAAAAAAAAAAAATCACTGAATAGTTCCATGCTTCCTAGAATCCCAAAGACTAAATCAAGCAGATGCAGGCCTTATATTCCAGCTTTCTCCCTGATCTGACCTGCAGACAGTATTTCCCAAACCATGTTCCACAGGACCTGCTGTCACAGTTGGCTTTGCAGCATTCTCCATGTGGTTCACACACCACAGGCTGTCTGCATGGACGCTGTAAATTTCTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCC...	GAGCCATGATCATGCCACTGCACTATTGCCCATGCCAGTCTGGGCAAGAGACTGAGACCCTGTCTCAAAAAAAAAAAAAAAAATCACTGAATAGTTCCATGCTTCCTAGAATCCCAAAGACTAAATCAAGCAGATGCAGGCCTTATATTCCAGCTTTCTCCCTGATCTGACCTGCAGACAGTATTTCCCAAACCATGTTCCACAGGACCTGCTGTCACAGTTGGCTTTGCAGCATTCTCCATGTGGTTCACACACCACAGGCTGTCTGCATGGACGCTGTAAATTTCTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCC...
Task1_train_48407	A mutation on Chromosome 22 has been found. Is it harmful or harmless? What disease, if any, does it cause?	Benign	CATGTCCGCATCCCAGAAGTGACCGCTAGGACAGTGGTGCTGTTGGCGATAACACTGCCCTTCCTCCAGCAGTGTCTGACAACTCGTGGAGGGATTTTTGGTGTCTTCATAGGTGGTGGAGGCTGCACGGACACTCCAAGGGCCGAGGCCAAGAATGTTAAACCTTCTGCAAGGGAAAGAGCTGTCCTGCCCCAAATGCCAGTAGCCCCTCGGTGAGAAACACACACTTCCAGAAACATGTAGGAAGGACAACTCAGGCTGCTCAACGATCTCTTGTACTTGAAGAGACGCCTGCAGCTCGGGCTGGATTTGACTGGTGT...	CATGTCCGCATCCCAGAAGTGACCGCTAGGACAGTGGTGCTGTTGGCGATAACACTGCCCTTCCTCCAGCAGTGTCTGACAACTCGTGGAGGGATTTTTGGTGTCTTCATAGGTGGTGGAGGCTGCACGGACACTCCAAGGGCCGAGGCCAAGAATGTTAAACCTTCTGCAAGGGAAAGAGCTGTCCTGCCCCAAATGCCAGTAGCCCCTCGGTGAGAAACACACACTTCCAGAAACATGTAGGAAGGACAACTCAGGCTGCTCAACGATCTCTTGTACTTGAAGAGACGCCTGCAGCTCGGGCTGGATTTGACTGGTGT...
Task1_train_48408	A mutation on Chromosome 22 is under review. Please evaluate whether this mutation is benign or pathogenic and specify the disease if necessary.	Benign	TAAAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTTTTGGCCTCAAGTGATCCGCCCACCTCAGCCTCCCAAAGCGTTGGGATTACAGGCGTGAGCCACCGCACCCGGCTCTTCACTTTTAAGAGACTGTTTTTCATTCTGTATAGCACTGAATGCTACTTTTAATTATCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCACCATCTCCCAGGCTGGAGTGTACTGGTGTGATCTCAGATCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATTCTCCTGTGTGAGCCACCGTGCCTGGCCTTTAT...	TAAAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTTTTGGCCTCAAGTGATCCGCCCACCTCAGCCTCCCAAAGCGTTGGGATTACAGGCGTGAGCCACCGCACCCGGCTCTTCACTTTTAAGAGACTGTTTTTCATTCTGTATAGCACTGAATGCTACTTTTAATTATCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCACCATCTCCCAGGCTGGAGTGTACTGGTGTGATCTCAGATCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATTCTCCTGTGTGAGCCACCGTGCCTGGCCTTTAT...
Task1_train_48409	A genomic change on Chromosome 22 is noted. Classify this variant as benign or pathogenic, and name the disease if relevant.	Benign	AAACGTTTGAGGTGATGAATACCTTCATTACCCTGATTTGATCATTGCACATTGTATGCATGTATCAAAGTATCACATGTAACACATAAATATGTACAATTACTATGTATCTATAAAAATAAGAAACAAAGGAAAACAGTTGCTGTATAAACAATACTGGGATAACTGTCAAAATTTAAATATTGAATATATTATATATGGGAAAATTGTACGGATATGAAATTATCTGAATTTGGTAATAATTGCACTGGGGTTATGTATGAAAACATCTTTGATCCTATGAGGTTCATATTGAATTATTTAGAGCTGAAGAATGTCAA...	AAACGTTTGAGGTGATGAATACCTTCATTACCCTGATTTGATCATTGCACATTGTATGCATGTATCAAAGTATCACATGTAACACATAAATATGTACAATTACTATGTATCTATAAAAATAAGAAACAAAGGAAAACAGTTGCTGTATAAACAATACTGGGATAACTGTCAAAATTTAAATATTGAATATATTATATATGGGAAAATTGTACGGATATGAAATTATCTGAATTTGGTAATAATTGCACTGGGGTTATGTATGAAAACATCTTTGATCCTATGAGGTTCATATTGAATTATTTAGAGCTGAAGAATGTCAA...
Task1_train_48410	A mutation on Chromosome 22 is under review. Please evaluate whether this mutation is benign or pathogenic and specify the disease if necessary.	Benign	AAACAGTTGCTGTATAAACAATACTGGGATAACTGTCAAAATTTAAATATTGAATATATTATATATGGGAAAATTGTACGGATATGAAATTATCTGAATTTGGTAATAATTGCACTGGGGTTATGTATGAAAACATCTTTGATCCTATGAGGTTCATATTGAATTATTTAGAGCTGAAGAATGTCAATCTCTTCAATTTACTCTCAAGTAGTCCAGCAAAAGAAAAAAAGTGATTGTGTAAATATATACACATATATACTGTGTACTCACACATACACATAGATGTGTGTGTATGAGAGAGAAAATTAGTGAAGGAAGGC...	AAACAGTTGCTGTATAAACAATACTGGGATAACTGTCAAAATTTAAATATTGAATATATTATATATGGGAAAATTGTACGGATATGAAATTATCTGAATTTGGTAATAATTGCACTGGGGTTATGTATGAAAACATCTTTGATCCTATGAGGTTCATATTGAATTATTTAGAGCTGAAGAATGTCAATCTCTTCAATTTACTCTCAAGTAGTCCAGCAAAAGAAAAAAAGTGATTGTGTAAATATATACACATATATACTGTGTACTCACACATACACATAGATGTGTGTGTATGAGAGAGAAAATTAGTGAAGGAAGGC...
Task1_train_48411	A mutation on Chromosome 22 has been found. Is it harmful or harmless? What disease, if any, does it cause?	Benign	TGCCCGGTAGAAAACCGCCATTGCTCACTCCCCCCACCCCCACAACACACCTTATGAAAATGCCCCTCTCTCCTCCAAAGGAGAAATGGCACATTAAAAGGCAGGATGTGTCTTGCTCCTTGCCCCAGGCTGGCTTCAGAATAAATTCACATTTGTGTATAAAACCTTTTGTATCACATTTTTTTTTGTATCAGAGTTAGTTGAGCTCTACACGCAGTGAGCAGCTCCTCAGCTTTTCGCTGCATAGGTACTGTGTTCAGCTTTCCTTCCGTCCTCAGTCTGGAGAACCTCAATCAACCTAGCTCCAGGTTTATGGATTC...	TGCCCGGTAGAAAACCGCCATTGCTCACTCCCCCCACCCCCACAACACACCTTATGAAAATGCCCCTCTCTCCTCCAAAGGAGAAATGGCACATTAAAAGGCAGGATGTGTCTTGCTCCTTGCCCCAGGCTGGCTTCAGAATAAATTCACATTTGTGTATAAAACCTTTTGTATCACATTTTTTTTTGTATCAGAGTTAGTTGAGCTCTACACGCAGTGAGCAGCTCCTCAGCTTTTCGCTGCATAGGTACTGTGTTCAGCTTTCCTTCCGTCCTCAGTCTGGAGAACCTCAATCAACCTAGCTCCAGGTTTATGGATTC...
Task1_train_48412	This sequence change occurs on Chromosome 22. What is the medical significance of this variant — is it benign or linked to a disease?	Benign	GGGAGAGAATGGCTAATGAGGCTCTAGGGATCAGCACAGCCAGCTGCTGGAGGTCCCAGAGGACGGGTGACTCAGCAGGAATGGGGGAGTCTGAGGGGTTGACAGAGTGCCCAATTCTCACCTCCTCCTGCACCTTCCAGAGAGACGGGCTGCAGGGAGTGATTGAGTGGATGAACATGACTAGAGGGACCCAGTCTTCTCCTCAGCAGCTGCTTGAGGACAGTATTAGCGGTCCCCTCAATCCCCCCCCCAACACATGCACACATGCACTGACCTGCAGGGGCCAGATCCCGGTGGACCCGGGGACACAGCTTCCAGGG...	GGGAGAGAATGGCTAATGAGGCTCTAGGGATCAGCACAGCCAGCTGCTGGAGGTCCCAGAGGACGGGTGACTCAGCAGGAATGGGGGAGTCTGAGGGGTTGACAGAGTGCCCAATTCTCACCTCCTCCTGCACCTTCCAGAGAGACGGGCTGCAGGGAGTGATTGAGTGGATGAACATGACTAGAGGGACCCAGTCTTCTCCTCAGCAGCTGCTTGAGGACAGTATTAGCGGTCCCCTCAATCCCCCCCCCAACACATGCACACATGCACTGACCTGCAGGGGCCAGATCCCGGTGGACCCGGGGACACAGCTTCCAGGG...
Task1_train_48413	Mutation context: Chromosome 22. Determine if this variant is likely to be benign or pathogenic. Mention the disease if applicable.	Benign	CCTCCACAATTTGCTGAGGGAGGCCCCAGAGTCCAGGGCACCCAGAGTGCTAACTAGCCCCTGGGGGTACAGGGAGAACAGCATGCTGTGTGGGGGATACTACTCTCTGCCCATACCTAGGGCCCTGTGGCGGCCACAGGCAGCACTGCTTATGCAGAGGCACTGGGGTGAGAAGGAGTAGGGTGCAGTAGTGAGGGCTCCACAGAGGGTGGAAGGGCTGCAGGGGAAGGCAGACCAGCAGGGATGCCATGAGGGCCTCAGATGCCAGGCTGCAGAGGTGGACGGGCTGGCCAGCTCCTCTCCCCAGCCTCCTACTGTAA...	CCTCCACAATTTGCTGAGGGAGGCCCCAGAGTCCAGGGCACCCAGAGTGCTAACTAGCCCCTGGGGGTACAGGGAGAACAGCATGCTGTGTGGGGGATACTACTCTCTGCCCATACCTAGGGCCCTGTGGCGGCCACAGGCAGCACTGCTTATGCAGAGGCACTGGGGTGAGAAGGAGTAGGGTGCAGTAGTGAGGGCTCCACAGAGGGTGGAAGGGCTGCAGGGGAAGGCAGACCAGCAGGGATGCCATGAGGGCCTCAGATGCCAGGCTGCAGAGGTGGACGGGCTGGCCAGCTCCTCTCCCCAGCCTCCTACTGTAA...
Task1_train_48414	This genomic variant is located on Chromosome 22. Can you determine its pathogenicity and name any linked disease?	Benign	GCTCTGGAACCTGGCTGCCCTGCCCCAGTGCATGTGGGATCCACGGCATGCTTCCTGCTTCGTCCTCTGCAGCCAGTAGGGGACTCCTGTGGCCAGGACTTCCTTGTTAAGTAGCAGCCCTTCTCCAAGGGGAGCACAAGCCTGCCCGCACACAGCCTCCAGCATCATGCTCCAGCAGGCCAAGCTCAGGGACAGGCAATTCAGTAACAAAACTCACAGCTCTGGACAGTTCTGGCACAAAGGTCAAGTCTGTCTGTGGGCAACTCAAGATTCTCATTCCACATGGGATGGAAAAAATGGGTCTCCAGCCACAGTGTGAG...	GCTCTGGAACCTGGCTGCCCTGCCCCAGTGCATGTGGGATCCACGGCATGCTTCCTGCTTCGTCCTCTGCAGCCAGTAGGGGACTCCTGTGGCCAGGACTTCCTTGTTAAGTAGCAGCCCTTCTCCAAGGGGAGCACAAGCCTGCCCGCACACAGCCTCCAGCATCATGCTCCAGCAGGCCAAGCTCAGGGACAGGCAATTCAGTAACAAAACTCACAGCTCTGGACAGTTCTGGCACAAAGGTCAAGTCTGTCTGTGGGCAACTCAAGATTCTCATTCCACATGGGATGGAAAAAATGGGTCTCCAGCCACAGTGTGAG...
Task1_train_48415	A variant was discovered on Chromosome 22. What is its functional impact — neutral or pathogenic? State the disease if pathogenic.	Benign	GGGCAGTCCCTCCCAGGTACCACTGTTCCCAGAACCAAGCCAGGTCCAGCTGCATTTTCTTGAGGCCCAATAACGAGAAGCAGACAAACTAGGAAAGAAGGGAGTTTATCACTGTAACTGGATACAGGGAGAAGGCTGGAGATAATTCCAGCAGACCAACTCAAAGTGCTACAATTTTCTTACTGTTTATATAGGTTGGGGTTATGTGCCTACATGCAGTACAGCAATCACCTAAGTCTACTGGTAACTAATTTTGTTCCAAGGAGAAGGTCAGAGGCAAAAAAAATGCTTGCTAAGTCCGATTAAAAGGGGCCCAGTGC...	GGGCAGTCCCTCCCAGGTACCACTGTTCCCAGAACCAAGCCAGGTCCAGCTGCATTTTCTTGAGGCCCAATAACGAGAAGCAGACAAACTAGGAAAGAAGGGAGTTTATCACTGTAACTGGATACAGGGAGAAGGCTGGAGATAATTCCAGCAGACCAACTCAAAGTGCTACAATTTTCTTACTGTTTATATAGGTTGGGGTTATGTGCCTACATGCAGTACAGCAATCACCTAAGTCTACTGGTAACTAATTTTGTTCCAAGGAGAAGGTCAGAGGCAAAAAAAATGCTTGCTAAGTCCGATTAAAAGGGGCCCAGTGC...
Task1_train_48416	This variant is located on Chromosome 22. Evaluate its biological effect and specify any disease association.	Benign	CTTGAGGCCCGACCACCGGCCCGACCACAAGCTTGGAGCCAAAACCCAGCACCGGCTGCTGGTGGTGCCCGAGAACGAGAACAGGATGGAGGACAGGCTGGCCGAGACCTCCAGGGCCAAAGACCATCACATCTCCGGAGCTGAGGTGGGGAAAGCAAGCACCTAGCATGACAATGGCCCCGTTGTGTGTGGTGGGGGTCGGGGTTGGGGGGCATGGTGCAGTCGGCCTTCACGTAAACTAAGTAGGCAGGTAGGATCTGAAGAAGGCACAGGTGCAAGTAAAATTCGTCAATTAAACCACTATTTTGATTACGTTCCAT...	CTTGAGGCCCGACCACCGGCCCGACCACAAGCTTGGAGCCAAAACCCAGCACCGGCTGCTGGTGGTGCCCGAGAACGAGAACAGGATGGAGGACAGGCTGGCCGAGACCTCCAGGGCCAAAGACCATCACATCTCCGGAGCTGAGGTGGGGAAAGCAAGCACCTAGCATGACAATGGCCCCGTTGTGTGTGGTGGGGGTCGGGGTTGGGGGGCATGGTGCAGTCGGCCTTCACGTAAACTAAGTAGGCAGGTAGGATCTGAAGAAGGCACAGGTGCAAGTAAAATTCGTCAATTAAACCACTATTTTGATTACGTTCCAT...
Task1_train_48417	Here is a mutation located on Chromosome 22. Determine whether it’s benign or pathogenic. If the latter, what disease does it cause?	Benign	GCATGAAAACCCCAGGAGGAAGCAGGGGACCCTCACCCATGGGCAGGTTCACAGTAGCCTAGAGGCCAGGGCTGGACCCCAGGGGTCCAAGGCCACCATCCGTGGAGCAGTCCCCTCTGCTGGGGAGCACCCTGGTGCAGAGACTGAGGATCGCTGAGCTGTGCTCCTCTCAAAGACAGCTGTACCCTAAATACCCCCTCGCTGGGAAGGAAGAAGAAGGGACAGCTCCTTGTTGGGTGTGGGAGTGGAGCCAAGGTGGACTTGAGACTCTGGGCGGCTTCTGTGGTATTTGAAGTTGCTAGTTTCTCAGTATCAGCGCG...	GCATGAAAACCCCAGGAGGAAGCAGGGGACCCTCACCCATGGGCAGGTTCACAGTAGCCTAGAGGCCAGGGCTGGACCCCAGGGGTCCAAGGCCACCATCCGTGGAGCAGTCCCCTCTGCTGGGGAGCACCCTGGTGCAGAGACTGAGGATCGCTGAGCTGTGCTCCTCTCAAAGACAGCTGTACCCTAAATACCCCCTCGCTGGGAAGGAAGAAGAAGGGACAGCTCCTTGTTGGGTGTGGGAGTGGAGCCAAGGTGGACTTGAGACTCTGGGCGGCTTCTGTGGTATTTGAAGTTGCTAGTTTCTCAGTATCAGCGCG...
Task1_train_48418	This mutation occurs on Chromosome 22. Does this change lead to a known medical condition, or is it benign?	Benign	CCAAGAAGTCCAGGTGGCGTCACCTCTCAAGATCACCTGAGGTCAGGAGTTTGAGAACAGCCTGCCCAACATGGTAAAACCCTGTATCTATTAAAAATACAAAAATGAGCCGGGCGTGGTGGCAGGCACCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCTCGAGGCTGGGAGGCGGAGGTTGCAGTGAGCCAAGATCGCGCCACTGCACTCCAGCCTGAGTGACAGAGTGAGACTCCGTTTCAAGAAAAATAATAATAAAACAAAAAAAGAAGAGAAAACTGAAGCTGAGATTCCGCCACAAGCTCCA...	CCAAGAAGTCCAGGTGGCGTCACCTCTCAAGATCACCTGAGGTCAGGAGTTTGAGAACAGCCTGCCCAACATGGTAAAACCCTGTATCTATTAAAAATACAAAAATGAGCCGGGCGTGGTGGCAGGCACCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCTCGAGGCTGGGAGGCGGAGGTTGCAGTGAGCCAAGATCGCGCCACTGCACTCCAGCCTGAGTGACAGAGTGAGACTCCGTTTCAAGAAAAATAATAATAAAACAAAAAAAGAAGAGAAAACTGAAGCTGAGATTCCGCCACAAGCTCCA...
Task1_train_48419	A variant has been detected on Chromosome 22. What is its effect — pathogenic or benign? If pathogenic, name the disease.	Benign	CCACAAGCTCCAGGATAGCTGGTTGGCGTGCTGTGCTGCACAACCTGAAAGAAGCGCCCACCGGATGCCAGGCACCTGCCATGGACCACTTGGTCGGGAGGAAACATGATGTCCATTGTATGGATGGGATAACGAGGTTCACAGCGGTGACACCCCTAGCCCACATGGAGAGAGACAGTGAATGGCTGAGCTGGGGTGCCCCCCGTGTGAGTTAGCAAGCTCCCCTGCTCAGGCTGCTGCTGGCCCAGCCCTATGGCTAAGTGGATTCCTGCTATCGTGTGCCCCAAATACAGATTGGATGTCGTCCATCTGATTGGACC...	CCACAAGCTCCAGGATAGCTGGTTGGCGTGCTGTGCTGCACAACCTGAAAGAAGCGCCCACCGGATGCCAGGCACCTGCCATGGACCACTTGGTCGGGAGGAAACATGATGTCCATTGTATGGATGGGATAACGAGGTTCACAGCGGTGACACCCCTAGCCCACATGGAGAGAGACAGTGAATGGCTGAGCTGGGGTGCCCCCCGTGTGAGTTAGCAAGCTCCCCTGCTCAGGCTGCTGCTGGCCCAGCCCTATGGCTAAGTGGATTCCTGCTATCGTGTGCCCCAAATACAGATTGGATGTCGTCCATCTGATTGGACC...
Task1_train_48420	This variant is located on Chromosome 22. Evaluate its biological effect and specify any disease association.	Benign	CTCCATTTTGCCTGGGCTGGTCTTGAACTCCTGACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGAGATTACAGGCCCTTCACCCCCTTGTTTTCTTTTTGTTTGTTTGTTTTTTAAAGACAGGGTCTCGCTCTTTGCCTAGGCTGGAGTGCAGTGCCCCGATCACAGCTCACCCCGATCACAGCTCACTGCAGCCTTGACCTCCTGGGCTCAGGTGATCTTCCCACTTCAGCCTTCCAAGTAGCTGTGATTACAAGTGCATGCCACACACTCGGCTAATATTTTTTAGTTTTTTGATAGAGATGGGGGTCT...	CTCCATTTTGCCTGGGCTGGTCTTGAACTCCTGACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGAGATTACAGGCCCTTCACCCCCTTGTTTTCTTTTTGTTTGTTTGTTTTTTAAAGACAGGGTCTCGCTCTTTGCCTAGGCTGGAGTGCAGTGCCCCGATCACAGCTCACCCCGATCACAGCTCACTGCAGCCTTGACCTCCTGGGCTCAGGTGATCTTCCCACTTCAGCCTTCCAAGTAGCTGTGATTACAAGTGCATGCCACACACTCGGCTAATATTTTTTAGTTTTTTGATAGAGATGGGGGTCT...
Task1_train_48421	This mutation on Chromosome 22 may be significant. Is it associated with any clinical condition, or is it benign?	Benign	AGCCAGACACATTTACCCTCCAGTTATGTCTCACTGGGAACTCAGACTCCAGATAACGTCTAGGAGGTCTTGATTATGCTCACTAAGCAGATCCATAGCTCAGAAGGGAGGAGGGGAGGGGCAGAGCCACACTCAGGCCACCTCCCTTAGAAAAGACTTTGCCAGGAGACAGAATGCTTGTTCTGGACATCAGAGAGGTCGGTGCCACAATCAACTTGAAACACCAGAAGATCCCTGGGAATTGTGGGCCTGTCACTCACTTTAAAATTACTACAGTGGCGATATTGAGATATCTAGTGTGCTTAAATGACCTCATCTTG...	AGCCAGACACATTTACCCTCCAGTTATGTCTCACTGGGAACTCAGACTCCAGATAACGTCTAGGAGGTCTTGATTATGCTCACTAAGCAGATCCATAGCTCAGAAGGGAGGAGGGGAGGGGCAGAGCCACACTCAGGCCACCTCCCTTAGAAAAGACTTTGCCAGGAGACAGAATGCTTGTTCTGGACATCAGAGAGGTCGGTGCCACAATCAACTTGAAACACCAGAAGATCCCTGGGAATTGTGGGCCTGTCACTCACTTTAAAATTACTACAGTGGCGATATTGAGATATCTAGTGTGCTTAAATGACCTCATCTTG...
Task1_train_48422	This is a variant located on Chromosome 22. Is this mutation a likely cause of disease or not?	Benign	ACAATAACCATAAGTATAGGGGAATCTAGGTCCTCCAGGTGGCTTCACACTTAGGGTCTTACTTCTCCCCCAGCATGCTGCAGTAAGAATTCGGCCTCTCAATCAGTCTTGTAGTAGTGAAGTTCTGCTATCATTATATTCTAATTCAAAATACTCAAATTCACAGATGAAGGCTAGAAATGGTTTGTTCACAACTACCCCTTGAAAGACAAGAAAAATTCTTTCAAGGACAAGCAACTTGAAAGTCTTTATCTACTCAGGAACAGATCCAGTCTCTGAACAATTTATCCAAATGAAATAAACCCAAGAAAAAGCCATAT...	ACAATAACCATAAGTATAGGGGAATCTAGGTCCTCCAGGTGGCTTCACACTTAGGGTCTTACTTCTCCCCCAGCATGCTGCAGTAAGAATTCGGCCTCTCAATCAGTCTTGTAGTAGTGAAGTTCTGCTATCATTATATTCTAATTCAAAATACTCAAATTCACAGATGAAGGCTAGAAATGGTTTGTTCACAACTACCCCTTGAAAGACAAGAAAAATTCTTTCAAGGACAAGCAACTTGAAAGTCTTTATCTACTCAGGAACAGATCCAGTCTCTGAACAATTTATCCAAATGAAATAAACCCAAGAAAAAGCCATAT...
Task1_train_48423	Chromosome 22 is altered by this variant. Does this mutation result in a disease or is it benign?	Benign	CCTTTGCCTGTCAACAGTCAGACAGGCCAGAATCAGGCCCTGGGCTGGAGGAGTCTCCCTGGGTTGATTTCTGTGCTACAGTGCTGTCAGCAGAGTGGGGTGGGGGAGGGGGAGGCGCGCTTTTTTCATCTACCCGGGGAGCAAACACCAACTCCTGCAGCAGTTCTGCCAACAAGGCAGAACTATGACGAAACTGATTACCACTAGCCTCTCTGTATCAGAGTCAAGATATGGGGTGGATGAGTCCGTTCCCCAAGGGTGTGCTTTGGAGCCACTGCCACAGAGCTAAGAAGCCCCTCTGCTAGAACACACCTGTGCCC...	CCTTTGCCTGTCAACAGTCAGACAGGCCAGAATCAGGCCCTGGGCTGGAGGAGTCTCCCTGGGTTGATTTCTGTGCTACAGTGCTGTCAGCAGAGTGGGGTGGGGGAGGGGGAGGCGCGCTTTTTTCATCTACCCGGGGAGCAAACACCAACTCCTGCAGCAGTTCTGCCAACAAGGCAGAACTATGACGAAACTGATTACCACTAGCCTCTCTGTATCAGAGTCAAGATATGGGGTGGATGAGTCCGTTCCCCAAGGGTGTGCTTTGGAGCCACTGCCACAGAGCTAAGAAGCCCCTCTGCTAGAACACACCTGTGCCC...
Task1_train_48424	A variant affecting Chromosome 22 has been observed. Determine if it's benign or associated with disease.	Benign	AGGAGTAACCTGGACAAGCTGTACCATGGCCTGGAACTCGCCAAGAAGCAGCTGCGAGCCACCCAGCAGACCATTGCCAGCTGCCTTTGCACCAACCTCGTCATCTCCCAGGGGCCTTTCCTGTACTGCTCTCTCATGGAGGTCAGGCTTCCCACAGAGCACAGGCGCCTGGTCACAGCACCAGTGGCTTCGTCTGACCATCTGTCTCGCCTCCGCAGGGCACTCCAGATGTCATGCTGTTCTCTAGGCCGGCATCCCTAAGCCTGCTCAGCAAACACCTGCTCAAGTCCTTTGTGTGTTCGGTGAGGGGCCAGGCGGGT...	AGGAGTAACCTGGACAAGCTGTACCATGGCCTGGAACTCGCCAAGAAGCAGCTGCGAGCCACCCAGCAGACCATTGCCAGCTGCCTTTGCACCAACCTCGTCATCTCCCAGGGGCCTTTCCTGTACTGCTCTCTCATGGAGGTCAGGCTTCCCACAGAGCACAGGCGCCTGGTCACAGCACCAGTGGCTTCGTCTGACCATCTGTCTCGCCTCCGCAGGGCACTCCAGATGTCATGCTGTTCTCTAGGCCGGCATCCCTAAGCCTGCTCAGCAAACACCTGCTCAAGTCCTTTGTGTGTTCGGTGAGGGGCCAGGCGGGT...
Task1_train_48425	Mutation context: Chromosome 22. Determine if this variant is likely to be benign or pathogenic. Mention the disease if applicable.	Benign	CCGATGAGGAGAGCGGCCTCTGGTCAGGGGTCGCACAGCCTAGTGGGCCTGGGCCCTGGGAGAGGGGTCGCCCTCCTTCTCTCACCCCACTCCTGATTTTATGCAGGAAGCTTTTTTAATGGAAAAGATGGGGCCCTGCAAGGGGGCTGGAGAAAGAGGCTTTATGGAGTCCAGGCCAGTGAGGTCGCTGGGCAGGCACCTAAGGAAAGAGAACCTAAACCCAGATCTTTTGCCACTTGGAGCTCATTCCTGGCAGTTGCCAATGGGTCACAGCCTCCTCTTGGCCCAGTGACCCAGCCTCATCTTGGAATTAAGGGTTT...	CCGATGAGGAGAGCGGCCTCTGGTCAGGGGTCGCACAGCCTAGTGGGCCTGGGCCCTGGGAGAGGGGTCGCCCTCCTTCTCTCACCCCACTCCTGATTTTATGCAGGAAGCTTTTTTAATGGAAAAGATGGGGCCCTGCAAGGGGGCTGGAGAAAGAGGCTTTATGGAGTCCAGGCCAGTGAGGTCGCTGGGCAGGCACCTAAGGAAAGAGAACCTAAACCCAGATCTTTTGCCACTTGGAGCTCATTCCTGGCAGTTGCCAATGGGTCACAGCCTCCTCTTGGCCCAGTGACCCAGCCTCATCTTGGAATTAAGGGTTT...
Task1_train_48426	A mutation has occurred on Chromosome 22. What is the medical relevance of this mutation?	Benign	TCCCCCTACCCCACAACAGTCCCCGGAGTGTGATGTTCCCCTTCCTGTGTCCGTGTGTTCTCATTGTTCAATTCCCACCTATGAGTGAGAACATGCGGTGTTTGGTTTTTTGTCCTTGCGATAGTTTGCTGAGAATGATGGTTTCCAGTTTCATCCATGTCCCTATGAAGGACATGAGCTCTTCATTTTTTATGGCTGCATAGTATTCCATGGTGTATATGTGCCACATTTTCTTAATCCAGTCTATCGTTGTTGGACATTTGGGTTGGTTCCAAGTCTTTGCTATTGTGAATAGTGCTGCAATAAACATACGTGTGCAT...	TCCCCCTACCCCACAACAGTCCCCGGAGTGTGATGTTCCCCTTCCTGTGTCCGTGTGTTCTCATTGTTCAATTCCCACCTATGAGTGAGAACATGCGGTGTTTGGTTTTTTGTCCTTGCGATAGTTTGCTGAGAATGATGGTTTCCAGTTTCATCCATGTCCCTATGAAGGACATGAGCTCTTCATTTTTTATGGCTGCATAGTATTCCATGGTGTATATGTGCCACATTTTCTTAATCCAGTCTATCGTTGTTGGACATTTGGGTTGGTTCCAAGTCTTTGCTATTGTGAATAGTGCTGCAATAAACATACGTGTGCAT...
Task1_train_48427	This variant is found on Chromosome 22. What is the clinical effect of this variant — benign or pathogenic? State the disease if applicable.	Benign	CCTCCTCCTGGCCCATGCAACACAGGGCTCAGCAGGGGAAACGCCTCTCCTTCGATGTGCACCATGGGCCGATGCCCTGCCCAGCACGCCACAGCCACGCCAACCACTCCCTGTTCCTGGTTCTCCCTTCTGCTCTCACTTTCCAATTCATTAATACCTGGTCCCCCTTTTGCTTTAACTTTTCAATTCATCAATCCGGTCAAGTTCATCTCTGGACTGGAACATGCCCCATAAATTACAGTCCTAAGTTCCAGCAGCTGTTTCCCAAACACACCAGGAGAGACGAGGCAGATCTGGGCCAGGACGGCAGGAGGGCCCCT...	CCTCCTCCTGGCCCATGCAACACAGGGCTCAGCAGGGGAAACGCCTCTCCTTCGATGTGCACCATGGGCCGATGCCCTGCCCAGCACGCCACAGCCACGCCAACCACTCCCTGTTCCTGGTTCTCCCTTCTGCTCTCACTTTCCAATTCATTAATACCTGGTCCCCCTTTTGCTTTAACTTTTCAATTCATCAATCCGGTCAAGTTCATCTCTGGACTGGAACATGCCCCATAAATTACAGTCCTAAGTTCCAGCAGCTGTTTCCCAAACACACCAGGAGAGACGAGGCAGATCTGGGCCAGGACGGCAGGAGGGCCCCT...
Task1_train_48428	This sequence change occurs on Chromosome 22. What is the medical significance of this variant — is it benign or linked to a disease?	Benign	ACAGAACAATCTGAGGAATTAAAGTCATATTTTTATTGCACCATAAAAACATGTGAAGGCGGCAGGACGGCGGCCGCGGGGCCAGGCGGAGAGCACCCGGCTCTGGCCCCACCCTGCACTCCCTGGGCCGTCTCCAGGGAGACGCAGGATCGAAACCACTGTTGGCCCAGCACACCGGTCCCACGCTGGGCAAGGGAGACCGGGAGAGCGGCCGCTTTGCCCACATTGCCCTGCTGGGCCCTGGTTCCTGCCCTGGCTGTGCAGCTGCCTGGGTGGGGGCTCTGGGCCAGTGTCCCACCAGAGTAGTGAGGTGTGGGGAT...	ACAGAACAATCTGAGGAATTAAAGTCATATTTTTATTGCACCATAAAAACATGTGAAGGCGGCAGGACGGCGGCCGCGGGGCCAGGCGGAGAGCACCCGGCTCTGGCCCCACCCTGCACTCCCTGGGCCGTCTCCAGGGAGACGCAGGATCGAAACCACTGTTGGCCCAGCACACCGGTCCCACGCTGGGCAAGGGAGACCGGGAGAGCGGCCGCTTTGCCCACATTGCCCTGCTGGGCCCTGGTTCCTGCCCTGGCTGTGCAGCTGCCTGGGTGGGGGCTCTGGGCCAGTGTCCCACCAGAGTAGTGAGGTGTGGGGAT...
Task1_train_48429	Consider a variant on Chromosome 22. Determine its clinical classification and disease relevance.	Benign	GCCATGCTCTGCAGGACAGACCCTGTCCCACCCAGGCCTGGGACCCCCGTAAACCACAGCAGCAGAGCAGGCATCAGGCAATCCAAGCAGCCAGGCCAGGCACAGCAAACCTGGGTGGACGTAGCTCACCCACAACAAATGGTGGAGGCAAGAATGGGTGAGCAGGAGGCCACCTGGGCTCCCTCAGGCACCCTGGTGTTTGCTTGGCCCTCACTGGAGCAAGGCCGCTGTGGCCACACCGGAGCCGGAGCTGTTGGACAAAGGCTTTCAGCACCCCTGAAGGGCTCGACAGCGTGTCCGGGGCTGCGGCCAAGTAAAAA...	GCCATGCTCTGCAGGACAGACCCTGTCCCACCCAGGCCTGGGACCCCCGTAAACCACAGCAGCAGAGCAGGCATCAGGCAATCCAAGCAGCCAGGCCAGGCACAGCAAACCTGGGTGGACGTAGCTCACCCACAACAAATGGTGGAGGCAAGAATGGGTGAGCAGGAGGCCACCTGGGCTCCCTCAGGCACCCTGGTGTTTGCTTGGCCCTCACTGGAGCAAGGCCGCTGTGGCCACACCGGAGCCGGAGCTGTTGGACAAAGGCTTTCAGCACCCCTGAAGGGCTCGACAGCGTGTCCGGGGCTGCGGCCAAGTAAAAA...
Task1_train_48430	This variant is found on Chromosome 22. What is the clinical effect of this variant — benign or pathogenic? State the disease if applicable.	Benign	CTGTGACCTGAACCCCTGGGCTTCTGCCTCAGGCCTCCTGTGCTCTGCTCTCTGCCTGCTGGGTCCCCTCACCAGGCTTCTGTCTGGTTCCCAGGCTACCTGCCTGGAGGGTCACACCAGGAGGATTTCAAACAGGTTTCAAGTGGGGTCACTTGCCATCACTGTGCCCCACGAGGTACACTGTTGTGGGCGGCAGGGCTGGCCTTTCTCATCTGGGACATGCCACGTTGCTGTTCCCAAGGGGAGTGGTGAGTGGGTCTGTCCTGGTGTGCCTGGCCTGGGGACTGCCAGTGTCCTTACTTGGACACTCAATGAAAAGG...	CTGTGACCTGAACCCCTGGGCTTCTGCCTCAGGCCTCCTGTGCTCTGCTCTCTGCCTGCTGGGTCCCCTCACCAGGCTTCTGTCTGGTTCCCAGGCTACCTGCCTGGAGGGTCACACCAGGAGGATTTCAAACAGGTTTCAAGTGGGGTCACTTGCCATCACTGTGCCCCACGAGGTACACTGTTGTGGGCGGCAGGGCTGGCCTTTCTCATCTGGGACATGCCACGTTGCTGTTCCCAAGGGGAGTGGTGAGTGGGTCTGTCCTGGTGTGCCTGGCCTGGGGACTGCCAGTGTCCTTACTTGGACACTCAATGAAAAGG...
Task1_train_48431	Chromosome 22 is altered by this variant. Does this mutation result in a disease or is it benign?	Benign	TCTACCCGAGGGCACCAGAGGGCACGAGAAGGCTGGCTCCCTGGCGCTGACACGTCAGGCAACTGAGGCACAAGGCTGGCATTTCTGAACCTTGCCCCTCTGCAAACACAAGGGGGCGATGGTGGCACTCCAAGCAAAGGGGCGTGTGGGTGCTGCAGGAGGAGCACAGAGCACTGGCGCCCCTCCCCTCCCGCCCTGCAGATGCCGGAGGCCCCGCCTCTGCTGTTGGCAGCTGTGTTGCTGGGCCTGGTGCTGCTGGTGGTGCTGCTGCTGCTTCTGAGGCACTGGGGCTGGGGCCTGTGCCTTATCGGCTGGAACGA...	TCTACCCGAGGGCACCAGAGGGCACGAGAAGGCTGGCTCCCTGGCGCTGACACGTCAGGCAACTGAGGCACAAGGCTGGCATTTCTGAACCTTGCCCCTCTGCAAACACAAGGGGGCGATGGTGGCACTCCAAGCAAAGGGGCGTGTGGGTGCTGCAGGAGGAGCACAGAGCACTGGCGCCCCTCCCCTCCCGCCCTGCAGATGCCGGAGGCCCCGCCTCTGCTGTTGGCAGCTGTGTTGCTGGGCCTGGTGCTGCTGGTGGTGCTGCTGCTGCTTCTGAGGCACTGGGGCTGGGGCCTGTGCCTTATCGGCTGGAACGA...
Task1_train_48432	This sequence change occurs on Chromosome 22. What is the medical significance of this variant — is it benign or linked to a disease?	Benign	CTACGGCAGGAGGAGCGCTTGAGGCCAGGAGAGTTCGAGACCAGCCTGGGCAACATGGCAAAAGAAAAAATATATATATATATTTTAGATGGAGTCTTGCTCTGTCACCAGGCTGGAGTGCAGTGGCACGATCACGGCTCACTGCAACCTCCACCTCTTGGGTTCAAGCGATTACCCTGCCTTAGCCTCCTGAGTAGCTGGGACTACAGGCGCGCGCTGCCACACCCGGCTAGTTTTTTGTAGTTTAGTAGAGATGGGGTTTCACCACATTGGCCAGGATGGTCTCAATATCCTGACTTCGTGATCCGCCCGCCTCGGCC...	CTACGGCAGGAGGAGCGCTTGAGGCCAGGAGAGTTCGAGACCAGCCTGGGCAACATGGCAAAAGAAAAAATATATATATATATTTTAGATGGAGTCTTGCTCTGTCACCAGGCTGGAGTGCAGTGGCACGATCACGGCTCACTGCAACCTCCACCTCTTGGGTTCAAGCGATTACCCTGCCTTAGCCTCCTGAGTAGCTGGGACTACAGGCGCGCGCTGCCACACCCGGCTAGTTTTTTGTAGTTTAGTAGAGATGGGGTTTCACCACATTGGCCAGGATGGTCTCAATATCCTGACTTCGTGATCCGCCCGCCTCGGCC...
Task1_train_48433	Chromosome 22 is altered by this variant. Does this mutation result in a disease or is it benign?	Benign	TGCTGCTTTAATTTTTAAATTTTCTTACAAAAATTTAGGTGTTTACCAATAGTCTTATTTTGGCTTATTTTTAATGCTTTTTCTCAGTGTTTTTCTTCTGTTTCTGAGTCACGAACAGCAGGCACTGAAAGCAGTCCCCCAGCCACTGCCGAAGGTCAGTCCCGGAGGTGCTGCCCAGGCTCCAGGCAGATGCGGCAGCCCCGGCCCCAGCCAGCATGGGCTGGAGAAAGGCTCTCTACTGCACAGGGGCCTCACGTGACTGCAGGGCTCTGGGGAGGTGGGGCACCTGTAGCCTGACCCCCACCTTGCTGCTTCCAAAG...	TGCTGCTTTAATTTTTAAATTTTCTTACAAAAATTTAGGTGTTTACCAATAGTCTTATTTTGGCTTATTTTTAATGCTTTTTCTCAGTGTTTTTCTTCTGTTTCTGAGTCACGAACAGCAGGCACTGAAAGCAGTCCCCCAGCCACTGCCGAAGGTCAGTCCCGGAGGTGCTGCCCAGGCTCCAGGCAGATGCGGCAGCCCCGGCCCCAGCCAGCATGGGCTGGAGAAAGGCTCTCTACTGCACAGGGGCCTCACGTGACTGCAGGGCTCTGGGGAGGTGGGGCACCTGTAGCCTGACCCCCACCTTGCTGCTTCCAAAG...
Task1_train_48434	This mutation is located on Chromosome 22. Is it associated with a disease or is it a benign polymorphism?	Benign	CAGCTCTCACAAGGCACAAGCCCCACCACTGCACGGTTGGGGTGGGAACCAAGGAGGTGGGTCCCAGGAGAGTTTCTGTGGGGGCAGGAGGTGTGAAGGCAGGAGGTGAGGGGACATGCCCGAGGGGCGCAGCGTCAGCCTCCCTGCTATGGTAGAGACTGGGGAACCTGTCACAGTGTCTGGGCCTGATGCCTGGCTCCTGGGGCAAGCGTCTCAGCAGCTGCACTCCTGCCTACCGGGTGCTTTCCCAGGCGGTCGCAGGCCGAGTGGCCTCGTTCCTCCCGGGTTGAGCCTCACACTCTTCTCTTCCCAGGGGATGT...	CAGCTCTCACAAGGCACAAGCCCCACCACTGCACGGTTGGGGTGGGAACCAAGGAGGTGGGTCCCAGGAGAGTTTCTGTGGGGGCAGGAGGTGTGAAGGCAGGAGGTGAGGGGACATGCCCGAGGGGCGCAGCGTCAGCCTCCCTGCTATGGTAGAGACTGGGGAACCTGTCACAGTGTCTGGGCCTGATGCCTGGCTCCTGGGGCAAGCGTCTCAGCAGCTGCACTCCTGCCTACCGGGTGCTTTCCCAGGCGGTCGCAGGCCGAGTGGCCTCGTTCCTCCCGGGTTGAGCCTCACACTCTTCTCTTCCCAGGGGATGT...
Task1_train_48435	This variant is found on Chromosome 22. What is the clinical effect of this variant — benign or pathogenic? State the disease if applicable.	Benign	CCTCAGTCTGGCCTGATTTCATGGTCCCCAGCTGTACCCCGTGTTAGGTGGGTGGCAGGTGGCAATTTGCCCTGACATGGCACAGCAGGGCCTCTGCATGGCCCGCTGATTGCTCCTCACAGGCACCTACGGGCTGAGCAACGCGCTGCTGGAGACTCCCTGGAGGAAGCTGTGCTTTGGGAAGCAGCTCTTCCTGGAGGCTGTGGAACGGAGCCAGGCGCTGCCCAAGGATGTGCTCATCGCCAGCCTCCTGGATGTGCTCAACAATGAAGAGGCGTGAGTGGGCGGGTCCTGCTGGGGTGAGCCCCAGTGTCCCGCCA...	CCTCAGTCTGGCCTGATTTCATGGTCCCCAGCTGTACCCCGTGTTAGGTGGGTGGCAGGTGGCAATTTGCCCTGACATGGCACAGCAGGGCCTCTGCATGGCCCGCTGATTGCTCCTCACAGGCACCTACGGGCTGAGCAACGCGCTGCTGGAGACTCCCTGGAGGAAGCTGTGCTTTGGGAAGCAGCTCTTCCTGGAGGCTGTGGAACGGAGCCAGGCGCTGCCCAAGGATGTGCTCATCGCCAGCCTCCTGGATGTGCTCAACAATGAAGAGGCGTGAGTGGGCGGGTCCTGCTGGGGTGAGCCCCAGTGTCCCGCCA...
Task1_train_48436	Located on Chromosome 22, this mutation has been observed. What is its biological consequence — is it benign or pathogenic, and which disease is associated if any?	Benign	GAGGGAGTGGCTGCTGTCTGGTGTGCAGGGGTCGGTGGGTTCCTCAGGGGCATTTCTGCCGACTTGGGCTGAGTCAGAGGCTTGGGAAGAGGGGGCGGCCGATGGTCTGTGGCTGGGAAGTGTGAGGGTCTCTCGCCTTGGGTCTGTGTCAGTTCTGGCAGTGACAGGGTGTTTGGGGGAAAGACTTGGGTCTGCCGCTACCCACAGGGGACTCTCAGGAACCCGAGAGCTTGGGGAGATGAAATGGGGGTGCATAGGGGCCACCTGTTGGCTCAGGGCCCTGTGGGGGCCGCTGAACCTGCTGGAACTCTCCTGCCTGC...	GAGGGAGTGGCTGCTGTCTGGTGTGCAGGGGTCGGTGGGTTCCTCAGGGGCATTTCTGCCGACTTGGGCTGAGTCAGAGGCTTGGGAAGAGGGGGCGGCCGATGGTCTGTGGCTGGGAAGTGTGAGGGTCTCTCGCCTTGGGTCTGTGTCAGTTCTGGCAGTGACAGGGTGTTTGGGGGAAAGACTTGGGTCTGCCGCTACCCACAGGGGACTCTCAGGAACCCGAGAGCTTGGGGAGATGAAATGGGGGTGCATAGGGGCCACCTGTTGGCTCAGGGCCCTGTGGGGGCCGCTGAACCTGCTGGAACTCTCCTGCCTGC...
Task1_train_48437	Here’s a variant located on Chromosome 22. What is the predicted biological effect — harmless or disease-causing?	Benign	TGGCAGTGACAGGGTGTTTGGGGGAAAGACTTGGGTCTGCCGCTACCCACAGGGGACTCTCAGGAACCCGAGAGCTTGGGGAGATGAAATGGGGGTGCATAGGGGCCACCTGTTGGCTCAGGGCCCTGTGGGGGCCGCTGAACCTGCTGGAACTCTCCTGCCTGCCACATGCCAGGGGCAGGGCTGAGGGAGTGTGAGGGATGCACAGCTGTTCAGGGCTGAGACATTCTGGGCTGGGGCTGTCCCAGCGTGGGAGGCGTGCGGGCTGTAGGGCCCCGAAGCTGACCTCCACCTTTCTGCTTCTCTCTCACGGACGCCGC...	TGGCAGTGACAGGGTGTTTGGGGGAAAGACTTGGGTCTGCCGCTACCCACAGGGGACTCTCAGGAACCCGAGAGCTTGGGGAGATGAAATGGGGGTGCATAGGGGCCACCTGTTGGCTCAGGGCCCTGTGGGGGCCGCTGAACCTGCTGGAACTCTCCTGCCTGCCACATGCCAGGGGCAGGGCTGAGGGAGTGTGAGGGATGCACAGCTGTTCAGGGCTGAGACATTCTGGGCTGGGGCTGTCCCAGCGTGGGAGGCGTGCGGGCTGTAGGGCCCCGAAGCTGACCTCCACCTTTCTGCTTCTCTCTCACGGACGCCGC...
Task1_train_48438	Consider a variant on Chromosome 22. Determine its clinical classification and disease relevance.	Benign	CTGAACACATACCTGAACCAGAAAGCAAGAAAGTGCTCACAGAATGATGGGGCGGCATCTAAAGGTGCCTGGAGCGCCCCCAACTGGCCACACATGGCACAGTCTGGGCATTAAGGAATAATGAGCCATGCGCTTGGGATTAGTAAACTACATACATCTTACAGCTCAATAAAAAATTTTAAAAAGACAATCGCCCAGACATTTAGGGGAAGAAGTAATGCCAATTCTACACAAACTCTTCTGGAAAACTGAAGAGGAGAGAACACTTCGAAACTCATCCTATAAGGCTGGCAAAAACCCTGATACCCAAACCAGATATT...	CTGAACACATACCTGAACCAGAAAGCAAGAAAGTGCTCACAGAATGATGGGGCGGCATCTAAAGGTGCCTGGAGCGCCCCCAACTGGCCACACATGGCACAGTCTGGGCATTAAGGAATAATGAGCCATGCGCTTGGGATTAGTAAACTACATACATCTTACAGCTCAATAAAAAATTTTAAAAAGACAATCGCCCAGACATTTAGGGGAAGAAGTAATGCCAATTCTACACAAACTCTTCTGGAAAACTGAAGAGGAGAGAACACTTCGAAACTCATCCTATAAGGCTGGCAAAAACCCTGATACCCAAACCAGATATT...
Task1_train_48439	Chromosome 22 is altered by this variant. Does this mutation result in a disease or is it benign?	Benign	TTGCTAATGATACCGACAAGGCACGCTAACGCGGACACTGTACACGACATCGCTAATGAGGACACCGTATAAGACATCGCTAGTAACTATCGCAAGAACAAAAAACCAAACACTGCATATTCTCACTCATAGGTGGGAATTGAACAATGAGATCACATGGACACAGGAAGGGGAATATCACACTCTGGGGACTGTTGTGGGGTGGGGGGGGGAGGGATAGCATCGGGAGATATACCTAATGCTAGATGACGAGTTAGTGCGTGCAGCACACCAGCATGGCACATGTATACATATGTAACTAGCCTGCACAATGTGCACAT...	TTGCTAATGATACCGACAAGGCACGCTAACGCGGACACTGTACACGACATCGCTAATGAGGACACCGTATAAGACATCGCTAGTAACTATCGCAAGAACAAAAAACCAAACACTGCATATTCTCACTCATAGGTGGGAATTGAACAATGAGATCACATGGACACAGGAAGGGGAATATCACACTCTGGGGACTGTTGTGGGGTGGGGGGGGGAGGGATAGCATCGGGAGATATACCTAATGCTAGATGACGAGTTAGTGCGTGCAGCACACCAGCATGGCACATGTATACATATGTAACTAGCCTGCACAATGTGCACAT...